一、基本信息

姓名：张华

学位：硕士研究生

职称/职务：高级实验师

邮箱：zhanghuamy@sit.edu.cn

办公电话：021-60873416

通讯地址：上海市奉贤区海泉路100号

二、学习工作经历

学习经历：

2006年09月-2009年03月 东华大学   有机化学专业 硕士2001年09月-2006年06月 齐鲁工业大学 生物工程专业 学士

工作经历：

2022年10月-至今 上海应用技术大学 香料香精化妆品学部 高级实验师2019年08月-2022年09月 中国科学院上海有机化学研究所 生命有机国家重点实验室  高级实验师

2009年03月-2019年08月 中国科学院上海有机化学研究所 生命有机国家重点实验室  助理研究员

三、主要业绩

学术论文（代表性即可，不超过10项）

1.Lin Zhang , Lantian Liu , Yefeng Zhou , Yan He, Xizhan Sun, Hua Zhang *, Xia Ma*.A data fusion system based on attenuated total reffectance mid-infrared spectroscopy and colorimetry combined with chemometrics for monitoring the fermentation process of Candida utilis.Talanta 294 (2025) 128163.

2.Yefeng Zhou^＃, Hua Zhang^＃, Yan He , Xia Ma*. Monitoring Tremella fuciformis submerged fermentation using ATR-MIR combined with chemometrics.Food Chemistry. 482 (2025) 144027. 3.Yefeng Zhou , Zilong Zhang , Yan He , Ping Gao , Hua Zhang *, Xia Ma *.Integration of electronic nose, electronic tongue, and colorimeter in combination with chemometrics for monitoring the fermentation process of Tremella fuciformis.Talanta 274 (2024) 126006.

4.Zhihan Liu , Yan He , Hua Zhang * , Xia Ma*.Layer-by-layer self-assembly embedding of nattokinase in chitosan/ γ -polyglutamic acid: Preparation, fibrinolytic activity, stability, and in vitro digestion study. European Journal of Pharmaceutics and Biopharmaceutics  199 (2024) 114281.

5.Yuru Wang, Yan He, Hua Zhang*, Xia Ma *.Purification and characterization of lipopeptides produced by Bacillus subtilius and their antibacterial effects on Escherichia coli and Staphylococcus aureus.Process Biochemistry 146 (2024) 44–55.

6.Zheng Q, Guo Y, Yang L, Zhao Z, Wu Z, Hua Zhang, Liu J, Cheng X, Wu J, Yang H, Pan L, Liu W. Enzyme-Dependent [4+2] Cycloaddition depends on lid-like interaction of the n-terminal sequence with the catalytic core in PyrI4. Cell Chemical Biology. 2016, 23, 352–360.

7. Tian Z, Sun P, Yan Y, Wu J, Zheng Q, Zhou S, Hua Zhang, Yu F, Chen D, Mandi A, Kurtan T, Liu W. An enzymatic [4+2] cyclization cascade creates the pentacyclic core of pyrroindomycins. Nature Chemical Biology.2015, 11, 259–265.

8. Sun P, Zhao Q, Hua Zhang, Wu J, Liu W. Effect of Stereochemistry of avermectin-like 6,6-spiroketals on biological activities and endogenous biotransformations in Streptomyces avermectinius. Chembiochem.2014,15(5), 660–664.

9. Yan Y, Chen J, Zhang L, Zheng Q, Han Y, Hua Zhang, Zhang D, Awakawa T, Abe I, Liu W. Multiplexing of combinatorial chemistry in antimycin biosynthesis: expansion of molecular diversity and utility, Angewandte Chemie International Edition.2013, 52(47), 12308–12312.

10. Sun P, Zhao Q, Yu F, Hua Zhang, Wu Z, Wang YY, Wang Y, Liu W. Spiroketal formation and modification in avermectin biosynthesis involves a dual activity of AveC. Journal of the American Chemical Society. 2013, 135 (4), 1540–1548.